Session IX: Clinical advances and translational medicine

Chair: Patrizia Agostinis

09:00-09:30

R. Aqeilan, Jerusalem

Modeling and Characterizing WOREE Syndrome: from Basic Science to Translational Medicine

09:30-09:45

Y. Abdelwahab, Cologne

Targeting MLKL with small molecules to inhibit necroptosis

09:45-10:00

M. Vogler, Frankfurt

Mitochondrial apoptosis as facilitator of Natural Killer cell mediated immunotherapy

10:00-10:15

F. Wohlfromm, Magdeburg

Recombinant lactaptin analogon RL2 inhibits TRAIL-induced cell death in breast cancer cell lines by mitophagy

10:15-10:30

H. Bantel, Hannover

TNFR1 inhibition reduces lipogenesis and improves insulin resistance and fibrotic liver injury in NAFLD mice

10:30-10:45

B. Cappe, Gent

Extracellular vesicles from apoptosis, necroptosis and ferroptosis in L929 cells are all enriched in RNA binding proteinsCoffee break

10:45-11:15

Coffee Break

Session IXb: Clinical advances, neuroinflammation and translational medicine

Chair: Bertrand Joseph

11:15-11:45

A. Aschenbrenner, Bonn

Infectious disease, chronic inflammation and the potential impact on the brain

11:45-12:00

O. Gökce, Münich

Molecular characterization of the aging mouse white-matter reveals adaptive immune system as driver of oligodendrocyte loss

12:00-12:15

P. Androvic, Münich

Spatial Transcriptomics-correlated Electron Microscopy maps morphological and transcriptional responses to brain injury

12:15-12:30

K. Shkaryna, Munich

Optogenetic control of programmed cell death reveals the key role of bystander signaling in regulation of epithelial integrity and inflammatory response

12:30-13:00

J. Davila-Velderrain, Milan

TBA

13:00

Concluding Remarks by the Organisers, Poster Prize Award, Announcement of the next meeting

Pierluigi Nicotera & Gerry Melino