Wednesday 28/9

Wednesday September 27, 2017

12:30 – 19:00  -  Registration

13.00 – 15:30

Session 1a: Cell autonomous pathways modulating cell death -
CHAIR: Boris Zhivotovsky

13:00 - 13:15

Brief historical introduction by Boris Zhivotovsky


Ana MARTIN VILLALBA (Heidelberg, Germany)
Unravelling how CD95 decides between life and death


Inna Lavrik (Magdeburg, Germany)
Quantitative single cell analysis uncovers the life/death decision in the death receptor network


Dagmar Kulms (Dresden, Germany)
Cancer cells employ nuclear caspase-8 to overcome the p53-dependent G2/M checkpoint


Cristina Muñoz-Pinedo (Barcelona, Spain)
Starvation induces the Unfolded Protein Response and cell death by necrosis or death receptor-mediated apoptosis


Ken CADWELL (New york, USA)
Autophagy and the intestinal barrier
Jessie GUO (New Jersey, USA)
Inhibiting autophagy as a cancer therapy for Kras-driven lung cancer

Sponsor presentations

Caroline Boeckx (Roche)
Evaluation of the tumor microenvironment
Sofia Vikstrom (Agilent)
Measuring metabolic phenotypes using the Agilent Seahorse XF Technology

15.40 – 16:15

Coffee break

16:15 – 18:30

Session 1b: Cell autonomous pathways modulating cell death -
CHAIR: Zahra Zakeri & Simone Fulda

Fabio MARTINON (Geneva, Switzerland)
Characterisation of a stress-response protease that contributes to proteostasis
Marcus CONRAD (Neuherberg, Germany)
Ferroptosis: mechanisms, in vivo relevance and therapeutic potential
Katherine Davies (Parkville, Australia)
Examining the role of the brace region in Mixed Lineage Kinase domain-Like protein (MLKL) oligomerisation and activation
Markus Rehm (Stuttgart, Germany)
Simulating and predicting cellular and in vivo responses of colon cancer to combined treatment with chemotherapy and IAP antagonist Birinapant/TL32711
Yves Dondelinger (Ghent, Belgium)
MK2 phosphorylation of RIPK1 regulates TNF-mediated cell death
Gianmaria Liccardi (London, UK)
The Mitotic Ripoptosome: an apoptotic and necroptotic cell death checkpoint during prolonged mitosis

Sponsor presentations

Toon De Roeve (Essen Bioscience)
IncuCyte® S3 - Live-Cell Imaging and Analysis around-the-clock
Martine Vanhoucke (BCCM/LMBP)
The Belgian BCCM/LMBP Plasmid Collection: a service by scientists for scientists
18:30 – 18:50
Official opening of the 25th Euroconference on Cell Death Research
Word by the rector of KU Leuven
18:50 - 20:00
ECDO Honorary and CDD Jurg Tschopp Prize - Lecture: Doug GREEN (Memphis, USA), introduced by the President of ECDO Seamus Martin
Targeting LAP: LC3-associated phagocytosis of dying cells in autoinflammation and anti-cancer immunityand back!

20:00 – 22:00

Opening reception (with drinks and bites and music)