Friday 30/9

Friday September 29, 2017

08:45 – 10:30

Session 4a: Cell death, tissue repair and microenvironment -
chair: Mauro Piacentini

08:45 - 09:00

Brief historical introduction by Mauro Piacentini

09:00 -09:30
Gabriele BERGERS (Leuven, Belgium)
Vascular and Immune conditioning to eradicate tumors
09:30 -10:00
Hector PEINADO (Madrid, Spain)
Influence of tumor-secreted exosomes in pre-metastatic niche formation
10:00 -10:15
Manuel Ehling (Leuven, Belgium)
PP2A/B55α regulates endothelial cell protection against apoptosis during vascular remodeling and pathological angiogenesis
10:15 -10:30
Aida Freire-Valls (Heidelberg, Germany)
Caspase-8 regulates postnatal angiogenesis via MAPK P38 and VE-cadherin

10:30 - 11:00

Coffee break

11:00 – 13:00

Session 4b: Cell death, tissue repair and microenvironment -
chairs: Patrizia Agostinis & Boris Turk

Massimiliano MAZZONE (Leuven, Belgium)
The killing kiss of phosphatase blockade in cancer 
Jannie BORST (Amsterdam, The Netherlands)
How to exploit the vaccine potential of radiotherapy
Anje Cauwels (Ghent, Belgium)
Targeting type I interferon activity to the tumor microenvironment or to dendritic cells synergizes with immunogenic chemotherapy to safely eradicate tumors
Marco Schaaf (Leuven, Belgium)
The role of endothelial cell-associated autophagy in melanoma growth
Olivier De Wever (Ghent, Belgium)
Radiotherapy-activated cancer-associated fibroblasts promote tumor progression through paracrine IGF-1R activation
12:45– 13:05
Flash talks -Session 2: P-3, 5, 9, 13, 45, 57, 63, 65, 73

13:05 – 15:45

Lunch on site + Poster session 2 (uneven poster numbers)

15:45 – 17:30

Session 5: Harnessing cell death and immunity crosstalk in translational medicine -
chairs: Klaus-Michael Debatin & Peter Krammer

15:45 - 16:00

Brief historical introduction by Klaus-Michael Debatin

Michael HENEKA (Bonn, Germany)
Microglial demise and the progression of Alzheimer’s disease
Andreas Linkermann (Dresden, Germany)
Necroptosis controls NET generation and mediates complement activation, endothelial damage and autoimmune vasculitis
Julia Zinngrebe (Ulm, Germany)
The linear ubiquitin chain assembly complex is a crucial regulator of toll-like receptor 3 signaling
Silvia Chiara FORMENTI (NY, USA)
Ionizing Radiation-Induced Immunogenic cell death
17:30 - 18:15
2nd Keynote Lecture: Alberto MANTOVANI (Rozzano, Italy)
The yin yang of tumor-associated macrophages in cancer progression
Poster and flash talk awards & Wrap-up

19:15– 20:30

Reception at the City Hall of Leuven (offered by the town of Leuven)


Conference dinner at Groot Begijnhof (for registered delegates)