Thursday September 29, 2016 |
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09:00 – 12:45 |
Session 2: Bcl-2 family, metabolism and cancerChair: Solange Desagher (Montpellier, France)
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09:30 -10:00
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Tony LETAI (Boston, USA)
Clinical success in targeting apoptosis in cancer cell mitochondria
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10:00 -10:30
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Jean-Claude MARTINOU (Geneva, Switzerland)
The mitochondrial pyruvate carrier: regulation of its activity in cancer cells
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10:30 -10:45
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Jerry Chipuk (New York, USA)
BAX-dependent mitochondrial outer membrane permeabilization: exquisitely regulated to the point of death.
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10:45 -11:00
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Mar Orzáez (Valencia, Spain)
The Bax transmembrane domain interacts with Bcl-2 proteins in non-apoptotic cells
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11:00 - 11:30 |
Coffee break |
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11:30 – 12:45 |
Session 2b: Bcl-2 family, metabolism and cancerChair: Philippe Juin (Nantes, France)
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11:30-12:00
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Jean-Ehrland RICCI (Nice, France)
Metabolic control of cell death
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12:00-12:15
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Patricia Gomez-Bougie (Nantes, France)
Repression of Mcl-1 and disruption of the Mcl-1/Bak interaction in myeloma cells couples ER stress to mitochondrial apoptosis
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12:15-12:30
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Sandrine Marchetti (Nice, France)
The oncogenic tyrosine kinase Lyn modulates Bim pro-apoptotic function
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12:30-12:45
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Prafull Kumar Singh (Freiburg, Germany)
Dynein light chain 1 mediated oligomerisation on mitochondria regulates the pro-apoptotic activity of the BH3-only protein Bim
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12:45 – 14:00 |
Lunch on site |
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14:00 – 15:30 |
Session 3: Stress and cell deathChair: Beatrice Bailly-Maitre (Nice, France)
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14:00-14:30
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Avi ASHKENAZI (San Francisco, USA)
Control of Apoptosis by the Unfolded Protein Response
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14:30-15:00
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Eric CHEVET (Rennes, France)
Antagonistic IRE1 RNase signals dictate glioblastoma tumor development
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15:00-15:15
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Susan Logue (Galway, Ireland)
Inhibition of IRE1a RNase activity modulates the secretome of Triple Negative Breast Cancer cells and enhances the effectiveness of chemotherapy
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15:15 -15:30 |
Beatriz Martín-Antonio (Barcelona, Spain)
Natural killer cells transfer antimicrobial and antitumoral Histone H2AZ to kill multiple myeloma cells contributing to transmissible cytotoxicity |
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15:30 – 15:50 |
Flash talks - Session 2Chair: Simone Fulda (Frankfurt, Germany)
Seung-Won Choi (poster Noh), Adrien Nougarede, Michaela Ohmer, Jinho Seo, Raquel Salvador-Gallego, Doaa Tawfik, Selma Tuzlak, Juan Garcia Valero, Sarka Vosahlikova, Tianqi Xu
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15:50 - 16:20 |
Coffee break |
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16:20 – 18:15 |
Session 3b: Stress and cell deathChair: Francois Vallette (Nantes, France) |
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16:20-16:50
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Boris TURK (Ljubljana, Slovenia)
Cysteine cathepsins: cell killing or tumor promoting in cancer?
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16:50-17:20
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Guido KROEMER (Paris, France)
Immunogenic cell stress and death in anticancer immunosurveillance
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17:20-17:35
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Raffaella Iurlaro (Barcelona, Spain)
Glucose deprivation induces ATF4-mediated apoptosis through TRAIL receptors DR4/TRAIL-R1 and DR5/TRAIL-R2
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17:35-18:15
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CDD Jurg Tshopp award presentation: Peter Vandenabeele (Ghent, Belgium)
Regulation of the core necroptosis pathway by nuclear events
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18:15- 20:15 |
Poster session 2(+ refreshments)
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