Thursday 29/9

Thursday September 29, 2016

09:00  – 12:45

Session 2: Bcl-2 family, metabolism and cancer

Chair: Solange Desagher (Montpellier, France)
 
09:30 -10:00    
Tony LETAI  (Boston, USA)
Clinical success in targeting apoptosis in cancer cell mitochondria
 
10:00 -10:30
Jean-Claude MARTINOU (Geneva, Switzerland)
The mitochondrial pyruvate carrier: regulation of its activity in cancer cells
 
10:30 -10:45
Jerry Chipuk (New York, USA)
BAX-dependent mitochondrial outer membrane permeabilization: exquisitely regulated to the point of death.
 
10:45 -11:00
Mar Orzáez (Valencia, Spain)
The Bax transmembrane domain interacts with Bcl-2 proteins in non-apoptotic cells

11:00 - 11:30

Coffee break

11:30  – 12:45

Session 2b: Bcl-2 family, metabolism and cancer

Chair: Philippe Juin (Nantes, France)
 
11:30-12:00
Jean-Ehrland  RICCI (Nice, France)
Metabolic control of cell death
 
12:00-12:15
Patricia Gomez-Bougie (Nantes, France)
Repression of Mcl-1 and disruption of the Mcl-1/Bak interaction in myeloma cells couples ER stress to mitochondrial apoptosis
 
12:15-12:30
Sandrine Marchetti (Nice, France)
The oncogenic tyrosine kinase Lyn modulates Bim pro-apoptotic function
 
12:30-12:45
Prafull Kumar Singh (Freiburg, Germany)
Dynein light chain 1 mediated oligomerisation on mitochondria regulates the pro-apoptotic activity of the BH3-only protein Bim

12:45 – 14:00

Lunch on site

14:00 – 15:30

Session 3: Stress and cell death

Chair: Beatrice Bailly-Maitre (Nice, France)
 
14:00-14:30
Avi ASHKENAZI (San Francisco, USA)
Control of Apoptosis by the Unfolded Protein Response
 
14:30-15:00
Eric CHEVET (Rennes, France)
Antagonistic IRE1 RNase signals dictate glioblastoma tumor development
 
15:00-15:15
Susan Logue (Galway, Ireland)
Inhibition of IRE1a RNase activity modulates the secretome of Triple Negative Breast Cancer cells and enhances the effectiveness of chemotherapy
  15:15 -15:30
Beatriz Martín-Antonio (Barcelona, Spain)

Natural killer cells transfer antimicrobial and antitumoral Histone H2AZ to kill multiple myeloma cells contributing to transmissible cytotoxicity

15:30 – 15:50

Flash talks - Session 2

Chair: Simone Fulda (Frankfurt, Germany)
 
Seung-Won Choi (poster Noh), Adrien Nougarede, Michaela Ohmer, Jinho Seo, Raquel Salvador-Gallego, Doaa Tawfik, Selma Tuzlak, Juan Garcia Valero, Sarka Vosahlikova, Tianqi Xu

15:50 - 16:20

Coffee break

16:20 – 18:15

Session 3b: Stress and cell death

Chair: Francois Vallette (Nantes, France)

 
16:20-16:50
Boris TURK (Ljubljana, Slovenia)
Cysteine cathepsins: cell killing or tumor promoting in cancer?
 
16:50-17:20
Guido KROEMER (Paris, France)
Immunogenic cell stress and death in anticancer immunosurveillance
 
17:20-17:35
Raffaella Iurlaro (Barcelona, Spain)
Glucose deprivation induces ATF4-mediated apoptosis through TRAIL receptors DR4/TRAIL-R1 and DR5/TRAIL-R2
 
17:35-18:15
CDD Jurg Tshopp award presentation: Peter Vandenabeele (Ghent, Belgium)
Regulation of the core necroptosis pathway by nuclear events

18:15- 20:15

Poster session 2

(+ refreshments)

 

 

                      

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